Acquired character getting golden yellow community staphylococcus infect have new fashion trend

Acquired character getting golden yellow community staphylococcus infect have new fashion trend
Acquired character getting golden yellow community staphylococcus infect have new fashion trend
The latest research of Wang Hui of BJ Union Hospital of Chinese Academy of Medical Sciences shows, the golden yellow staphylococcus of community's acquired character is infected with (CA-MRSA) Epidemiology characteristic appear new trend: --Every continent peculiar CA-MRSA cloned and began to spread to the other continents in the past. Such as cloning beginning to spread to Europe and Asia in U.S.A. some popular CA-MRSA. --Kill the toxin of leucocyte (PVL) Positive CA-MRSA, thought sensitive to most antibacterial medicines of kind in the past, and newest finding, CA-MRSA has already begun to obtain the new one and able to bear the medicine gene, such as being able to bear medicines to gentamicin and oxygen Fluorine sand star. --The incidence of CA-MRSA is stored in the difference of the region. In U.S.A., CA-MRSA occupies the first place in the community infects; A lot of country PVL positive CA-MRSA incidence in North Europe is very low; But in southern Europe, such as Greece, Algeria, CA-MRSA incidence is relatively high. --In some hotspots, CA-MRSA has already begun to sow to the hospital scatteredly, has become the important pathogens infected in the courtyard. And the appearance of this phenomenon, make it more difficult for clinicians to deal with CA-MRSA while infecting. Community, two MRSA all same CA-MRSA there is not a clear definition at present in the courtyard, generally adopt the definition of Center for Disease Prevention and Control of U.S.A.: CA-MRSA means in the clinic or is admitted to hospital MRSA of detection in 48 hours, there is no MRSA infecting or field planting history, not hold various conduits and other to pass the cover medical device before this, and not been in hospital in one year, operation, dialysing and attending to the history. The difference of MRSA lies in in CA-MRSA and courtyard found at present: ( 1) It has no patient of MRSA dangerous factor in the courtyard that CA-MRSA sees more, often appear in the skin or skin soft tissue is infected, seeing more children, athlete, prison prisoner, soldier, particular race, intravenous drug abuse person and homosexual crowd. MRSA sees more the persons who are in hospital for a long time, diabetic, dialysing patient and ICU to carry the patient of the intravenous thorough fare in the courtyard. ( 2) It is mainly because of the penicillin conjugated proteln of code (PBPs) that MRSA is able to bear the medicine mechanism Gene change due to. CA-MRSA usually only for ��- inner amides antibiotic last medicine, be cin to it whether if you can't begin, esters and ring third sand star,etc. Fluorine quinoline promise ketoneses intra-annulars big last medicine after waiting erythromycin to it w recentlied; It is able to bear medicines seriously that MRSA in the courtyard is usually multiple, , usually only to the peptide sensitivity of candy. ( 3) According to virulence gene carried, CA-MRSA usually carries PVL gene which kills the toxin of leucocyte encoded, PVL toxin can cause and occur frequently a series of serious diseases such as abscess, necrosis pneumonia, necrosis muscle membrane inflammation,etc.; MRSA does not usually include PVL gene in the courtyard. ( 4) According to hereditary background, CA-MRSA getting golden yellow staphylococcus V type usually; SCCmec of MRSA usually in the courtyard. In addition there are certain differences in some other member's characteristics. In main infection type 2000 when CA-MRSA caused, a MRSA of U.S.A. was prospective to discover, in 1100 MRSAs infect a patient, 12% are community's acquired character, 85% are the acquired character of the hospital. CA-MRSA patient the mean age is 23 years old, and MRSA patient the mean age is 68 years old in the courtyard. In addition CA-MRSA mainly sees to black person, the low-income one and children. According to infecting the type clinically, 75% of the CA-MRSA comes from the skin or soft tissue and infects, 6% come from the airway infection, 1% come from the urinary tract and infect. When it means CA-MRSA mainly concentrates on the soft tissue of skin to infect. In August of 2006, in " magazine of New England " reported 400 cases of skin soft tissue accepted in the emergency call of the teaching hospital of 11 universities of U.S.A. for medical treatment was infected, MRSA accounts for 59%, and 97% of the bacterial strain clones one for USA300 which produces PVL. It's time to work out the conclusion, CA-MRSA is the main pathogens in the skin soft tissue that an emergency call accepts for medical treatment is infected. Epidemiology of CA-MRSA of our country is indeterminate at present, need to carry on prospective clinical research. One that is with international exchange is frequent day by day, require us to enhance vigilance urgently, control the epidemiology development trend of CA-MRSA.


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