Can make blood platelet by inducing the multi-functional stem cell
Can make blood platelet by inducing the multi-functional stem cell
Tokyo, November 23 (Xinhua) ' Reporter Lan JianZhong) The researchers of Japanese Tokyo University announce, they develop and use inducing the multi-functional stem cell (iPS cells) Make the technology of the blood platelet, and the blood platelet that has confirmed being made out through animal's experiment has styptic functions. IPS cells are a stem cell with stronger potentiality of splitting up, " induced" by the genetic transformation by body cells such as skin cells,etc. Developed. Train the cell need, utilize the intersection of mankind and early period embryo, and can proliferate limitlessly, so the expected blood platelet used for producing in a large amount blood transfusion of new technology. The great research group led of river rattan of associate professor of Tokyo University, publish the thesis and say on the monthly magazine of " medical magazine of the experiment " of U.S.A. on the 22nd, they human skin fiber of use organize master cell and funicular blood cell to produce iPS cells at first, then add several kinds of blood cells and proliferate factor and nutrition cell, train the megakaryocyte that can make the blood platelet, make and bleed small board finally. Researchers are defeated by the little mouse the blood platelet produced, find the blood platelet concentrate on the injured blood vessel, form the thrombus, has given play to the function of the blood platelet normally. Researchers have used cMyc gene related to cancer, can make the megakaryocyte and produce the blood platelet high-efficiently. Because the nucleus which contain the hereditary information does not exist in the blood platelet, and the nucleus which mix the other cells among them can be through shining the radioactive rays and filtering, removing, so will not have risk of canceration at the time of clinical practice.
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