Alcohol of white birch ester can inhibit cholesterol and triglyceride from formating

Alcohol of white birch ester can inhibit cholesterol and triglyceride from formating
Alcohol of white birch ester can inhibit cholesterol and triglyceride from formating
It is reported ' Reporter Hu DeRong) Alcohol of white birch ester purified from the bark of the white birch, can inhibit cholesterol and triglyceride from formating, prevent obesity, artery porridge a kind of sclerosis and 2 type diabetes effectively. Chinese Academy of Sciences the intersection of Shanghai and the intersection of life and the intersection of research institute and biochemistry and the intersection of cell and the intersection of research institute and Song protect bright the intersection of seminar and relevant the intersection of research and thesis of scientific research personnel, publish in " the cellular metabolism " at the magazine recently. The expert thinks, newly discovered alcohol of white birch ester can be regarded as the guide compound of researching and developing the relevant medicine, can also exert an important influence in researching and developing and lowering the lipoprotein medicine. Known as clinic " Three Tenors " Hyperlipemia of the first, is shown as high cholesterol blood disease, high triglyceride blood disease. Among them, high cholesterol is a main cause of disease which causes atherosclerosis, coronary heart disease and cerebral apoplexy; High triglyceride is closely related to emergence of obesity, 2 type diabetes. In the human body, lipid such as cholesterol, fatty acid, triglyceride have a biosynthesis course, this course depends on a special protein molecule - -The transcription factor is come to activate. The long-term foundation discovers, are called " SREBP " Transcription factor,have to play a very important role activation route on it is here it is relevant. Song BaoLiang JingJie, the scientific research personnel such as being expensive Tang of seminar, through high compound screening of flux, find alcohol of white birch ester growing in the white birch bark of the North of our country is " SREBP " Activate specific inhibitor of the route. Pass and block " SREBP " under study for action The route, can reduce lipid such as cholesterol, fatty acid and triglyceride to formate. In animal's body, alcohol of white birch ester can reduce lipid level notably, prevent obesity, and improve the sensitiveness of insulin, there is good efficiency on 2 type diabetes and atherosclerosis. According to the introduction of scientific research personnel, this kind of function mechanism of lowering the lipoprotein compound is brand-new, lower a gleam of on it and it is clinical employ extensively by cholesterol medicine like " Lip river cut down his spit of fland " Compare, demonstrate even better efficiency similarly. Song BaoLiang researcher say the intersection of white birch and the intersection of ester and alcohol, and " whether Lip river cut down his spit of fland " when being interviewed by reporter Can reduce cholesterol level effectively, but alcohol of white birch ester can also reduce fatty acid and triglyceride level more prominently, the result to the 2 type diabetes is more obvious. It is reported, it is quite ripe to purify the craft of the alcohol of white birch ester from the bark of the white birch, Song BaoLiang seminar has already patented.


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