How to employ DC antitumor vaccine in treatment of cancer

How to employ DC antitumor vaccine in treatment of cancer
How to employ DC antitumor vaccine in treatment of cancer
Cao ZhiYu, the general hospital of PLA Headquarters of the General Staff (309 hospitals of PLA man) Intestines and stomach tumour professional group's group leader, associate professor of treatment of department of general surgery, study group's committee member and concurrently secretary in surgery of entire PLA, for cancers gastrointestinal, among make a diagnosis and give treatment quality that tumour because it if you can't take an advanced study, visit relatively, can't bear by 3 items about the scientific research task and 1 of field operations subjects surgicals of intestines and stomach tumour, obtain China's medical scientific award 1 second prize, 2 items medical achievement second prizes of entire PLA, 1 scientific and technical second prize of Beijing, 2 items army's medical achievement second prizes, the third-class project of gold bridge of Beijing rewards one. The time of paying a home visit: More every by Tuesday morning ' Change once every three months) Sequence call: (010)51520493, with the development of biotechnology, DC antitumor vaccine as surgery, set the intersection of chemotherapy and the intersection of tumour and treatment free, defend recuring, defending shifting, effective supplement of non-proliferation, not only behind it is for surgery,but also for in that later period can't perform the operation new treatment chance been offered to patient. Studying according to the amynologic expert of tumour, the cancer patient is because of one's own immune system defect or immune deterioration, it is unable to discern and remove the mutant cancer cell to cause, the ones that for cancer cell spread and grow with the machine that can be taken advantage of, with the constant growth of the quantity of cancer cell, it begins to fight for to grow nutrition and energy that the supersession need with normal cells, influence normal organism function of the human body, even cause the human organ and be unable to run well, cause necrosis and depleted of the organ. Researchers find, the immune system of the human body has complete monitoring functions, because tumour cells have resisting and inhibitory activity on immune system of the organism, make immune cell unable to discern and wound tumour cells. There is a kind of tree that has strong antigen to offer the function that dashes for ward the cells of the shape in the normal human body, known as DC cell, it is that the strongest full-time antigen of function passes and presents cells in the human body, it is equivalent to a messenger, transmit antigenic information to lymphocytes, stimulate internal initial type lymphocytes to activate, help to rebuild a tumour patient to monitor the function to the immunity of tumour cells, because it not merely has wounding the function of target tropism on tumour, and rebuild and repair the function, call this technology DC vaccine abroad. Then, in what case antitumor vaccine employ DC, how could give play to the role of its antitumor vaccine? PLA Headquarters of the General Staff general hospital ( 309 hospitals of PLA man of Beijing) Intestines and stomach tumour Cao Zhi house of professional group of department of general surgery passes the application in clinic of DC antitumor vaccine in recent years, patient separately from behind operations early and in patient two respect use for DC vaccine can't perform the operation on the later period make an introduction. To the patient performing the operation, the one that must draw tumour of the operation and organize DC antitumor vaccine different from immune treatment of other cells is, it needed after the operation the patient's tumour drew antigenic information while organizing, to have the intersection of messenger and the intersection of DC and cell of function go on outside the body inducing and banking up the bone with earth human body, make it support antigenic information of tumour, go back and is defeated by the tumour patient, as DC vaccine goes back to input in patient's body, it will pass antigenic information to present to the immune system, activates its immunological function, tell the immune system to carry on the attack of the target tropism to the cancer cell with such antigenic information. DC antitumor vaccine not only have any malicious side effect to the patient but also improved the patient's immunity, and is suitable for the treatment of tumour of any belly, so DC antitumor vaccine is the best and surgery, chemotherapy unites application together, can not only raise the cure rate of the operation but also reduce the poisonous side effect of chemotherapy. To the patient not performing the operation, the one that must use the tumour patient in later period in the poly- storehouse of antigen of tumour because of cancer cell is some and difficult to excise the operation to soak extensively, or some patients can't tolerate the patient of major operation with serious internal medicine department, DC tumour vaccine can play an anticancer role too. Its key technology lies in the poly- storehouse of antigen of tumour, make DC cells cause and form antitumor vaccine quickly. It is exactly different from ordinary immune treatment of biological cell: The killing the target tropism of cancer of first, it has determined this vaccine must use antigenic polypeptide of tumour to make DC cells cause quickly, train the biological cell treatment without target tropism to have essential differences with the blood of umbilicus; Second, must draw patients since the peripheral blood of the body as DC cells that is trained, but can't train with the allogenic blood; Third, this technology must be according with GMP and authorizing ten thousand grades of whole, some one hundred grades of ultra clean cells and treating the laboratory and banking up the bone with earth. PLA Headquarters of the General Staff general hospital ( 309 hospitals) Director Cao of the department of general surgery proposes the tumour patient in later period in condition progress arrives, though DC antitumor vaccine prevent from, recur, prevent from, shift and the intersection of non-proliferation and field make more greatly progress, but complicated because of the cause of disease of tumour, certain validity and different limitation exist in every therapeutic method at present, so, the treatment of malignant tumour can not make the clinical result that cures by a certain item of technology or method only, the individualized healing solution optimized synthetically is the first-selection of the cancer patient. Document / Duan YanJie


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