Infect plasmodium or can inhibit the metastasis of cancer of lung

Infect plasmodium or can inhibit the metastasis of cancer of lung
Infect plasmodium or can inhibit the metastasis of cancer of lung
It is reported ' Reporter Li TianShu) The biological medicine in Guangzhou of the Chinese Academy of Sciences and research institute Chen Xiaoping seminar and Guangzhou medical college of the health breathe the south mountain academician's subject of clock of research institute of disease and make up and make finding, after the little mouse of lung cancer model is infected with plasmodium, proliferating the process and is inhibited obviously of tumour cells. Researchers point out, if this research is proved effective, the clinic that can carry on lung cancer by exploring plasmodiums and infecting the route is treated. The relevant scientific paper has already been issued in U.S.A. <> is had. Malaria is a common insect-pollination infectious disease, it is causing the cause of disease of malaria that plasmodium is infected with, regard periodic shiver with cold, generating heat, splenomegaly,etc. as the characteristic clinically. In lung cancer immunization therapy experiment research that both sides launch jointly, researchers find, after the little mouse of lung cancer model is infected with plasmodium, proliferating the process and is inhibited obviously of tumour cells. Further discover, plasmodium is infected with and can promote the withering and dying of the little mouse tumour cells of lung cancer model, suppress the production with vascular tumour, through inhibiting growth and transformation of little mouse's lung cancer, can lengthen the existence time of the little mouse notably. Why is plasmodium infected with, inhibited the growth of tumour and shifted? Researchers find, plasmodium is infected with and can activate the natural immune system of organism, induce, produce a large amount of IFN - γ s ' A kind of interferon) With TNF - α' Necrosis factor of tumour) Wait, obviously strengthen the natural killer cell (NK cells) Wound activity. NK cell the intersection of organism and important immune cell, plasmodium infect can induce organism produce the intersection of tumour and some and the intersection of whole body and systemic tumour -specific immunoreaction, make about 10% of the little mouse tumours of model totally disappear.


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