It is still insufficient that vaccine prevents cervical cancer from following the medical evidence of the card

It is still insufficient that vaccine prevents cervical cancer from following the medical evidence of the card
It is still insufficient that vaccine prevents cervical cancer from following the medical evidence of the card
Staff reporter Wang Dan "Though with the cause of disease of cervical cancer - -People's papilla tumour and virus (HPV) Relevant and inferior type vaccine based on infecting prevents from studying and already deepening constantly, but HPV vaccine employs in the whole world and still at the starting stage, excessively propagates even expands its using value blindly inadvisably. " On " U.S.A.'s medical magazine " published in the near future, many clinical medicines and public health domain expert have carried on the discussion around the application of HPV vaccine and high benefit question of endangering the patient of cervical cancer abroad, and write articles and propose the above-mentioned view. At the national gynecological tumour academic meeting of the 11th time that will be hosted by Chinese Medical Association's gynecological tumour credit in the near future, the expert participating in the conference agrees on above-mentioned view. The expert points out, though HPV vaccine of our country is still at clinical research stage at present, but should draw the use experience of foreign HPV vaccine at the present stage, reason scrutinizes the value of HPV vaccine, propagate the public objectively. HPV infect mean, suffer from palace neck cancer " present the intersection of HPV and vaccine propagate mode, strengthen HPV, infect with causality with cervical cancer excessively, having weakened the important channel which cause cervical cancer of spreading through sex intercourse etc., amalgamating the high-risk group of cervical cancer of other dangerous factors of smoking etc. is nearly ignored. It is not just to propagate so. " On the 7th issue " U.S.A.'s medical magazine " of 2009 published in the near future, the American Mayor graceful duke defends institute's social medical science department Rothman professor to propose, HPV vaccine driven by the economic benefits more or less during marketing like other vaccine, popularize extensively " All girls suffer from cervical cancer risks " Idea,it is excessive it strengthen HPV infect with to public health and life the influences of quality, the one-sidedness exists. So, which kind of information is selected for use to carry on objective propaganda to HPV vaccine in any way, it is professional doctor and challenge which the medical domain expert faces at present. Director of BJ Union Hospital gynaecology and obstetrics Professor Shen Zhyuan agrees on above-mentioned statement. He explains, it is the most important causing the cause of disease to be plain of cervical cancer that HPV is infected with, this point has already been verified. HPV infects as the most common transfer of infection of sex, is up to 79% in the probability that women infect in all one's life. However, most HPV can be removed by the infeted's one's own immune system, a few women will develop into the intersection of continuation and HPV infect only, for the intersection of cervical cancer and pathological change or cervical cancer in front of the cancer a few possible progress. "That is to say, HPV means suffering from cervical cancer. " Shen Zhyuan says, the emergence of cervical cancer can be considered to be " seeds " (HPV infects) , " sunshine " (dangerous factor) And " soil " (ripe palace neck transforming area grow the upper skin) During complicated interaction result. Only many kinds of factors act on together, will cause the continuation HPV to infect, thus the palace happen on the neck cover inner tumour is turned into or cervical cancer. Have, study, reveal HPV infect 8 month skin inner tumour at the neck can take place palace 24 month on average continuously, after will not soak cancer from 8 years to 12ing. "Then, carry on HPV vaccine immunity to women of all infection HPV? How to weigh the pros and cons during vaccine immune result and bad reaction? When women have not confirmed yet after infecting for HPV and more than ten years when being young, the true result of HPV vaccine can only be fixed by clinical experiment and long-term following up a case by regular visits to. " Relevant experts say. It is unsuitable to treat coldly and sift and check " the idea of popularizing HPV vaccine extensively at present thinks " in early days, if has prevented HPV from being infected with, cervical cancer would not take place. But the actual conditions are not like this. HPV has 100 inferior type multi-type, among them 15 kinds are correlated with taking place in tumour at least. And in HPV vaccine employed in the whole world at present, one is 4 price HPV vaccines that Merck Company produced, directed primarily to HPV6, HPV11, HPV16, these 4 kinds of inferior virus of HPV18; Another one is 2 price HPV vaccines that Ge Lan plain SmithKline company produced, endanger the virus high only to two kinds HPV16, HPV18. " Norwegian medical magazine editor-in-chief Haug professor writes articles in " U.S.A.'s medical magazine ", raises questions to the benefit question of cervical cancer of wide application and preventing from of HPV vaccine. He propose, have following the intersection of card and medical evidence, indicating HPV vaccine can succeed in, prevent cervical cancer safely clear at present. Excessively popularize vaccine to use, thus cause cervical cancer to sift, check that is ignored, it is not the wise tactics. Chinese Medical Association gynecological the intersection of tumour and credit know General Board, Vice President of Tsing-Hua University medical college Cao ZeYi Professor, propose the same view too. Because the intersection of HPV and vaccine that the whole world use uncovered all HPV type leave at present, at the same time, extant HPV vaccine is preventative vaccine, to already infecting women of HPV invalid, so, can not prevent cervical cancer absolutely only by vaccine inoculation. Cao ZeYi proposes, unable to judge what women will develop into cervical cancer when infecting HPV at present. Moreover, even the continuation HPV takes place and is infected with, so long as make the cytologic inspection of palace neck regularly, pathological change before treating cancer correctly, the risk of developing into cervical cancer is still very low. So, regular cervical cancer is sifted, checked that should not be given up, especially in developing countries. "Our country should take general survey of cervical cancer as the core at the present stage. " ZeYi Cao claim different country, different and racial and HPV getting inferior to infect, the difference stores in also. Even in our country, HPV popular situation of different areas is not the same. For example, see to the north of the Changjiang River of our country more with HPV16 type, but as the main fact with HPV38 type to the south of the Changjiang River. So, should define main HPV type of this country or area left before using HPV vaccine, could prevent cervical cancer effectively only to this type other vaccine. "Our country does not have nationwide precise materials so far. " Cao ZeYi introduces, will have the intersection of tumour and credit more gynecological by Chinese Medical Association, women and children of Chinese Center for Disease Prevention and Control the intersection of health center,etc. and many of prevention and cure project, cervical cancer of China, that unit participate in, it is our country's only nationwide general survey project at present. This project is started in 2007, plan to finish the cervical cancer general survey of 100 million women in 10 years. The expert hopes, this data that project future must be published, can be regarded as HPV vaccine the basis developed and employed. Vaccine employed a section of way to go " Britain has launched the clinical controlled study. Observe, find by 5 year, inoculate and inoculate HPV vaccine palace of crowd the intersection of skin and inner tumour incidence, have prominent differences at the neck. So it inoculates HPV to be can effective to receive affirmation of medical circle already in vaccine. But, how many times does HPV vaccine need inoculating to produce and prevent function? Inject and need repeatedly How long does it want the interval? Prevent function how long Yes maintained? What crowd needs to inoculate? How to fix the best to inoculate age? These questions have not been clear yet, need further verifying. " Cao ZeYi says. It is introduced, prevention from suffering from the diseases and control centre of U.S.A. release the report to claim, report the data of the system according to the American vaccine bad reaction, June to will it be December 2008, 2006, U.S.A. is from 9 year old to 26? Yu  blame step and? HPV vaccine which 3 million pharmaceutical Merck Companies produced. 12424 bad reactions correlated to this vaccine happen during this period, the incidence is 53.9 / 100,000 pharmaceuticals. Among them, 772 (6.2%) It is a serious bad reaction, 32 people die. The report points out, the above-mentioned bad reaction statistical data do not have obvious difference compared with other vaccine. To the above-mentioned data, Shen Zhyuan says, in order to reduce the bad reaction correlated to HPV vaccine, the application of HPV vaccine should be directed primarily to women in the cervical cancer hotspot and high-risk group. For example, the disorder of sexual life, beginning sexual life (less than 16 years old) too early , women of giving a birth, prolific etc. in early years.


|