Disease accuses of centre's pursuing and capturing " The tick bites the disease " Arch-criminal

Disease accuses of centre's pursuing and capturing " The tick bites the disease " Arch-criminal
Disease accuses of centre's pursuing and capturing " The tick bites the disease " Arch-criminal
Li DeXin China's disease was accused of last September of virus chief in the centre, once " the tick bit the disease " to happening in Henan, Hubei, Anhui and other places for this newspaper The incident carries on the continuous observation report, initiate the society to pay close attention to. This kind of hard shell small worm which is known as the tick, where on earth to haunt? What terrible bacterium is carried on one's body? The pathogenic virus? The person bitten by tick's worm, will present serious generating heat ing, companion's blood platelet is reduced, do not even manage and die Just at the same time, China's disease accuses of virus chief Li DeXin and his research group in the centre in 6 field investigations having illness coming on in the province, from patient and local tick worm, separate a kind of new virus, it and inferior virus of Buddhist nun of cloth already found are similar, but gene sequence is different On March 17 this year, China's disease accuses of centre's announcing through the signed article that is published on the medical publication " medical magazine of New England " of international authority that is published this day, this reason " The tick bites the disease " And the new virus found, is named as generating heat by the Chinese scientist companion's blood platelet reduces the inferior virus (SFTSV) of Buddhist nun of cloth of syndrome ,Abbreviated as the inferior virus of Buddhist nun of new cloth. It, " the tick bites the disease " Arch-criminal. " chase the murderer " A infecting in the courtyard incident happened in Anhui in significant events 2006, a patient was once bitten by tick's worm before having illness coming on, and separate to on one's body " A cell of people has no physique " . Disease accuses of department's requiring that launches the relevant symptom patient " Whether bitten by the tick " Wait for epidemiology to investigate. Ministry of Public Health will make in 2008 <>,Instruct " the tick bite the disease " Discovery, report and treatment in the basic unit. Some " 2009s The tick bites the disease " The patient does not have " There is no physique " Infect the evidence. Researcher separate, like inferior virus, Buddhist nun of cloth, to one kind from patient, disease accuse of department until " whether tick bite disease " Turn from the bacterial infection to the virus to study. The virus will launch correctly in an all-round way in 2010 " The tick bites the disease " Aetiology study,investigate those scattered on hospitals regional "generate heat there aren't companion blood platelet " Patient, search the trace of the virus from it. The disease accused of department's investigating in national larger range in 2011 " Companion's blood platelet is reduced syndromically to generate heat " Distribution,new without being found out about for viral one ranges prevailing. Infecting the incident initiates " The tick bites the disease " Report The Beijing News: Paid close attention to extensively by the society last year " The tick bites the disease " Is it one kind that send disease newly? Li DeXin: " the tick bites the disease " It is commonly called as that ordinary people's future trouble to bitten by the ticking is ill. At the end of last century, USA and Europe and other places found " a cell of people does not have physique disease " ,The infeted all have history bitten by the tick. In 2001, in Daxing'an Mountainrange area of our country, were found too that was bitten by the tick, infected with " a cell of people did not have physique disease " Patient. But the above-mentioned case, all reveal that it is open-air animals to infect the source. The Beijing News: When does China's disease accuse of the centre to pay close attention to this kind of disease? Li DeXin: In 2006, a infecting in the courtyard incident happened in Anhui Province, there were 10 cases at that time, all generated heat companion's blood platelet reduced symptommed, have all found on the patients " A cell of people has no physique " Pathogen last evidence,besides first patient who has illness coming on, it is 9 other to have medical worker that be kept in close touch or accompany and attend to by relative as patients the first in patients, and does not have it the experience which the tick bites. Thought this epidemic situation at that time, it was a successor of person finding for the first time in the whole world's " a cell of people did not have physique disease " Epidemic situation. Later, disease accused of department's beginning to pay close attention to " a cell of people did not have physique disease " ,And require that launches " bitten by the tick " to the patient of the relevant symptom Wait for epidemiology to investigate. Because it is difficult to be perceived that tick's worm bites, and the initial symptom after having illness coming on, also shown as and had a high fever more, easy and other diseases are obscured. In 2008, Ministry of Public Health also makes <>,Instruct " the tick bite the disease " Discovery, report and treatment in the basic unit. The Beijing News: This newspaper when Hubei investigation, have doctor say according to have antibiotic therapeutic method, physique of disease too last year, a lot of ticks have bitten the disease patient and has been cured. Why does that turn the sight studied to the virus from the bacterium later on? And lock the inferior virus of Buddhist nun of cloth? Li DeXin: 2009, " the tick bites the disease " to report at the basic level in infectious disease The case, generate heat and reduce with the blood platelet a little, when the reduced case of leucocyte is further investigated, in the samples of a lot of patients, can not have nuclear acid and antibody with corresponding physique to measure, that is not to find " There is no physique " Evidence infected. Later, the intersection of infectious disease and the intersection of research and group, from a patient among them, separate, arrive one the intersection of cloth and inferior virus of Buddhist nun, but not totally identical with the inferior virus of Buddhist nun of cloth that is already found. The researcher calls it inferior virus of Buddhist nun of new cloth temporarily. Though just separate from a patient's body to the virus, still need to prove the relevance of the virus and cause of disease, but this clue, accuse of department disease to treat " the tick bites the disease " Sight,from bacterial infection turn to viral research. Will it be May 2010, virus launch until " whether tick bite disease " in an all-round way Aetiology study,relevant at network " physique" until disease accuse of Reporting the clue of the case, investigate those scattered in the regional hospital ones " companion's blood platelet is reduced to generate heat " Patient, search the trace of the virus from it. More than one hundred patients are infected with the new virus evidence The Beijing News: Whether is there virus research standard that such a world approves of, from isolating the same virus for the patient of the same symptom more or less, can confirm a kind of disease is caused by this virus? Li DeXin: Need separating to the virus from a large number of patients, but there is no concrete digital index, because the range that each kind of virus involves, it is the pathogenic rate, the number of people of the onset has difference greatly. Generally speaking, several hundred are more. The Beijing News: That, this time, researcher from how much piece " whether tick bite disease " All separate to the inferior virus of Buddhist nun of new cloth on the patients? Where are these patients distributed? Li DeXin: Because " the tick bites " It is a kind of experience difficult to be perceived, but some patients appear " to generate heat companion's blood platelet reduces syndrome " Symptom behind,to bite quilt tick when remembering. If so we collect in hospital in hospital mainly The case, some patients in them have the experience which tick's worm bit before having illness coming on. Measure through the laboratory, in the serum samples of more than 200 patients, find about 70% patient has evidence that inferior virus of Buddhist nun of new cloth infects, genes and/or antibodies separating virus, detection virus. These patients come from Hubei, Henan, Shandong, Jiangsu, Anhui and Liaoning, there are 6 provinces altogether, it is very wide to distribute, the Middle East Department and Northeast have, this it briefs new the intersection of cloth and Buddhist nun on to be may be very much extensive in range in inferior spread of virus too. " the tick bites the disease " Studying still needs to adjust more? ? The Beijing News: With the present result of study, can confirm " the tick bites the disease " Arch-criminal,is new for cloth for Buddhist nun inferior for virus? Li DeXin: Can confirm the inferior virus of Buddhist nun of new cloth generates heat companion's blood platelet reduces the cause of disease of syndrome. Main evidence have now, first, the intersection of companion and blood platelet reduce patient, separate arrive the same new inferior virus, Buddhist nun of cloth, in the body in generate heat by different area. Second, the majority generates heat companion's blood platelet reduces the syndrome patient to measure to the evidence that the inferior virus of Buddhist nun of new cloth infects in the body, including separating the virus, measure to virus gene and/or antibody, patient's convalescent antibody male genital has more than 4 times of rising to transfer degree to or drip, neutralize the male genital of antibody to rotate or drip degree and rise. Have not found the evidence that the virus infects in the health philtrum. Third, after inoculating the experimental animal with the virus, the animal reduces the blood platelet, the liver, kidney change the case. The following discoveries are briefed on tick's worm and involved in disease; Some patients have history bitten by the tick, separates from tick's worm to the inferior virus of Buddhist nun of new cloth, time slot and tick of onset time slot that worm haunt identical. Through a large number of investigations, have defined new cloth Buddhist nun's inferior virus pathogenic clinical manifestation and epidemiology characteristic. For example main symptom of patient generate heat and the intersection of digestive tract and symptom, blood platelet reduce and leucocyte reduce and liver renal function damage, some patients bleed to behave. This disease mainly happens in hills, mountain area, the patient takes adult peasant as the core, some patients have been bitten by the tick. Popular one of the onset is April - October, it is May - July that the peak prevails, this is the active time slot of tick's worm too. The Beijing News: " the tick bites the disease " Study,work of needing a lot also yes, do. Li DeXin: Yes, because last year was more urgent, the case which we study at present, all patients in hospital in the hospital, relative condition is relatively serious. Investigated and judges according to epidemiology before this, " the tick bites " And then there are some light disease cases, can recover without treatment, there are some patients very light in clinical manifestation, see the doctor only in the clinic, fully recover soon, does not exclude from having recessiveness to infect the case either. So we want work that make one of this year, to investigate " generate heat companion's blood platelet reduces syndrome " in national large range Distribution. Reagent box which measured the new virus has already distributed The Beijing News: To ordinary people, a kind of new virus, may mean one is undeterminable, but everywhere hidden danger. Everybody wants to know whether the inferior virus of Buddhist nun of new cloth is bitten and spread only through tick's worm, are there other spread channels? Li DeXin: This is a subject problem that scientific circles should be studied too, from the scientific aspect, find a kind of new virus, will find out its media and host soon. In fact the public cares about, where is new virus hidden? Through what routes spread. This year, we will launch the research work. At present, it has been already a specialized reagent box to measure inferior virus of Buddhist nun of new cloth that national disease accused of the centre, distribute to national every provincial disease and accuse of the centre, and launch the relevant training. We hope to improve the medical health organ in the basic unit right " Companion's blood platelet is syndromic to generate heat " Clinic find, it last ability,last ability and detection against virus, epidemiology. Accusing of the close cooperation of the department through medical organization and disease, we believe that will touch the spread range of the inferior virus of Buddhist nun of fresh cloth, further understand its danger. In addition, we have already announced the gene sequence of the inferior virus of Buddhist nun of new cloth, it is believed that foreign medical scientific circles will carry on relevant research to such new virus, understand whether there is this disease that exists in the locality. Perhaps international cooperation can help people to know such new virus faster. The Beijing News: The discovery of the inferior virus of Buddhist nun of new cloth, help " the tick bite the disease " Effect a radical cure? In addition " the tick bites the disease " Happen on some peasants of mountain area only at present, and public health have meaning to whole society? Li DeXin: We will investigate nationwide, understand popular range of such new virus, diseases caused are born. Confirm that propagates media and host of the virus. Pay close attention to as to the public " Companion's blood platelet is reduced syndromically to generate heat " ,There is not specific drug at present, the research against virus medicine is a work with very great difficulty, the whole world is studying, but make little progress. The more important thing is " generate heat companion's blood platelet reduce syndrome " ordinary people can understand, prevent Knowledge,can in lasting this disease and last corresponding treatment. Interview and write edition /staff reporter Wei Ming speech The Beijing News drafting / JunMing Lin


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