The essential change has not taken place in bird flu virus

The essential change has not taken place in bird flu virus
The essential change has not taken place in bird flu virus
The birds flow the touching successor has not found the precise evidence press spokesman of Ministry of Public Health Mao QunAn says at the news briefing that is held on April 11, it has already had a lot of reports abroad that people's bird flu family had illness coming on, but not found bird flu virus ( H5N1) at present The successors of people's epidemiology and biological precise evidence. Recently, the internationally recognized medical magazine " lancet " has been issued to the expert of our country to assembling research thesis having illness coming on of people's bird flu family together of Nanjing of Jiangsu Province of last December. The thesis claims that the successor of limited person of bird flu virus may taken place between two cases. Mao QunAn says, about this epidemic situation, Ministry of Public Health had already released relevant information last December. The result of study of gene sequence of virus reveals, two of virus gene sequence of ones that separate from two case respiratory tract samples is nearly totally the same. Studies have suggested two virus all key some location of gene sequence still the intersection of birds and source, have not found the successors of people's epidemiology and biological precise evidence. Mao QunAn claims, it is an important public health task at present to prevent and control people's bird flu epidemic situation. Ministry of Public Health further improved " China should plan to plan influenza largely and prevailingly with the emergency preplan " and " the people of Ministry of Public Health were infected with the high pathogenic bird flu emergency preplan " recently, cover China Mainland with all provinces while being sound further ' District, city) Influenza epidemic situation last network to be and early-warning system,it is monitor, last checking and administrative system not to last reason pneumonias unidentified, have strengthened the training of hygiene technical staff at the basic level such as countryside and urban community,etc., in order to find the suspicious case early, report, change the place of examination, treated and cured a patient and established the solid foundation in time. Meanwhile, Ministry of Public Health and the Ministry of Agriculture are improving the cooperation mechanism constantly, holds the association of dealers of the meeting to discuss regularly, notify information in time, has strengthened the joint defence to unite and accuse of. National the intersection of food and medicines supervise administration bureau start great to prevail the intersection of influenza and the intersection of vaccine and special examination and approval procedures. At present, our country is continuing international organizations such as strengthening and World Health Organization,etc. and the countries concerned exchange and cooperation in such aspects as information, technology. Reason that suspect highly, even so, reader pay close attention to the fact very much still to among them some question. Such as " limited person successor " What concept is it? Why is said " May happen " ? If " limited person successor " Confirm, mean bird flu virus steps into one step forward in evolution? For this reason, the staff reporter specially interviewed one of the authors of this research report, disease of Center for Disease Prevention and Control of China to control with Feng ZiJian, director of emergency processing office a few days ago. Feng ZiJian says, Center for Disease Prevention and Control of China, Jiangsu Province the intersection of Center for Disease Prevention and Control,etc. and expert of unit adjust in the intersection of " the lancet " and people of Nanjing city the intersection of bird flu and the intersection of case and epidemiology based on a large amount of of research report that magazine deliver Check and laboratory research. The same as the gathering epidemic situation of bird flu of the family of counting that was reported in the world in the past, the bird flu case of this pair of of father and son in urban area in Nanjing happens this time, also highly suspected that the successor has the limited person has happened. It is introduced, after this epidemic situation took place last December, Center for Disease Prevention and Control of China, Center for Disease Prevention and Control, Jiangsu Province cooperated closely, separate from the respiratory tract sample of two cases to H5N1 high pathogenic bird flu virus, carry on viral gene sequence determine and than right. The result reveals, the gene sequence of two of virus is nearly totally the same, and virus of birds' source. Generally speaking, people are from infecting with high pathogenic bird flu virus to have illness coming on, incubation period is 7 days on average. Feng ZiJian says, after second person's bird flu case of Nanjing is confirmed, epidemiology investigator investigate overall and careful track in two weeks and earlier life orbit before having illness coming on to the patient, have not found it and died of illness in the contact history of the birds, has not found its history of contact with poultry, have not found other reliable exposing the factor either. Can confirm, as first father of case, second case go on, attend to to son in being ill, such as wiping the phlegm, washing is suffered from diarrhoea the clothes that the thing polluting etc.. The death of the 8th day after having illness coming on of the first case, the second case has illness coming on in two days after dying of illness in first case. He attends to the son's time and has illness coming on time has not exceeded 7 days incubation period. Therefore, the investigator judges tentatively the second case is infected through keeping in close touch the first case. The case of Nanjing has not gone beyond and realized the epidemiology materials to reveal, from 1997 to the present previously, the whole world has already reported to and found 46 gathering person's bird flu epidemic situations of family, it accounts for 1/4 of nearly 400 cases already confirmed in the whole world to involve the case. The case mainly takes place in the country in Southeast Asia. The 60th World Health Assembly that summer of 2007 holds proposes clearly, the successor the limited person happened in bird flu, high pathogenic the intersection of bird flu virus and H5N1 can infect to people from animal, but also can in successor, wife of a certain limit. Just its chain of spread is very short, great majority are only limited to and infect the relative who kinsfolks kept in close touch. In October of 2007, in Pescadores area of Pakistan, 6 suspected person's bird flu cases have appeared in a family in succession, among them have 5 people who are brothers. Survey report that World Health Organization announce will it be December 27 2007 claim, can't get rid of in the patient these appearing limited the intersection of people and successor. What is meant by limited the intersection of people and successor? ZiJian Feng say limited the intersection of person and successor limit and can't take place people that human world travel effectively continuously infect the case very much promptly. In the epidemic situation of this Nanjing, up to several dozen persons keeping in close touch with the first case, include girl friend and mother of closer the first case than its father contacts. Observe and measure with the laboratory through tight medical science, has not found it infects. Carry on anaphase blood testing with two persons who keeps in close touch case to all, its bird flu H5N1 virus antibody is negative. Feng ZiJian points out, the appearance of case of this pair of father and son in Nanjing has not gone beyond the understanding of people's bird flu previously of scientific circles. Several typical cases reported in the world before this, the case is the close contact with direct blood relationship person. H5N1 capable of transmitting in human world until World Health Organization old to prevail the intersection of prewarning and division of issue to influenza 2005 at present, the whole world is at prewarning for third stage of period at present, by distributing the epidemic situation of the successor of case and limited person as the characteristic. Feng ZiJian says, the limited person appears successor's case does not mean the essential change takes place in bird flu virus. The continuously effective spread of human world happens to need biological foundation in bird flu. After this biological foundation mainly refers to the genetic mutation of bird flu virus, superficial glycoprotein its can until receptor at leather cells combine effectively on the people, thus make people infect. Global the intersection of bird flu and the intersection of epidemic situation and characteristic behave the reason why send out and not limited the present stage Person successor,it is because of bird flu virus been if you can't take place by the essence yet, make a variation. So far, including our country, high pathogenic bird flu virus ( H5N1) that all families in the world gather the case and separate It is birds' source, do not possess the ability to spread in human world continuously, effectively. Gather the case as to the family, 3 points of scientific circles realize at present: First, kinsfolks expose the birds or environment that bird flu virus pollutes to dying of illness at the same time, the common infection source has caused the family to gather the emergence of the venereal disease example; Second with blood relationship kinsfolks, may cause family gather the intersection of venereal disease and emergence of example by a certain the intersection of host and factor that know still, but present scientific research has not found such particular factor yet; Third, under specific circumstances, often close and long-time contact because between kinsfolks, lead to the fact limited the intersection of person and the intersection of successor and case take place, but this kind of spread has not changed the essential characteristic of bird flu virus at present, therefore can't cause the spreading each other of human world. Since the 2004, report limited the intersection of people and the intersection of successor and suspicious case in Indonesia, Pakistan, Thailand, Turkey country. This is that bird flu virus accelerates the mutant result in recent years on earth, there is or this kind of case, just found in recent years? Feng ZiJian says, can't say a plurality of countries report this kind of case is that bird flu virus accelerate the mutant result. At present, the infection, spread mechanism about bird flu virus have a lot of mysteries that fail to untie. Enhance vigilance, strengthen and monitor, finding in time, report and investigation people's bird flu case, and carry on genetic analysis to bird flu virus that people are infected with, it is to the dangerous keys of carrying on assessment and prewarning of successors of people of people's bird flu virus, also there is great and prevailing very important measure to people's bird flu and influenza of effects.


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