Sift out high and endanger a nasopharyngeal carcinoma patient and help the individualized treatment

Sift out high and endanger a nasopharyngeal carcinoma patient and help the individualized treatment
Sift out high and endanger a nasopharyngeal carcinoma patient and help the individualized treatment
It is reported ' The easy reporter gold of reporter Lee's weather is beautiful) A few days ago, the professor unites a research that Chinese Academy of Sciences, Chinese University of Hong Kong, Singaporean state-run general hospital,etc. finish together forever by Shao Jian of centre of prevention and cure of Zhongshan University's tumour, through to the nasopharyngeal carcinoma reviewing analysis and research of loud sample quantity, find that utilizes measuring the relevant gene of 7 pieces of nasopharyngeal carcinoma, can endanger being high a nasopharyngeal carcinoma patient to choose out from the ordinary patient, not merely can predict the risk and prognosis of surviving that a nasopharyngeal carcinoma patient recurs, can guide and implement more effective healing solution clinically. Since 2005, Shao builds the seminar forever, adopt the immunity to organize chemistry to dye technology, organize the sample to carry on research to 1268 nasopharyngeal carcinoma and tumour from areas such as Guangdong, Guangxi, Fujian, Hong Kong and Singapore,etc., in research or literature report and cause of disease of nasopharyngeal carcinoma that 18 are previous, are soaked and in shifting, tumour blood vessel is produced,etc. the relevant gene, select a closest gene after 7 survive with nasopharyngeal carcinoma patient in advance of latent membrane albumen of EB virus, combine the nasopharyngeal carcinoma patient's gender parameter, employ the bioinformatics method, set up mathematics, predict model, select 431 person high to endanger patient, return for being low to endanger the group while being other. Researchers follow up a case by regular visits to and follow the trail of finding in clinical 5 years, two groups of patients' existence state has prominent differences, classify as low to endanger the intersection of nasopharyngeal carcinoma and patient of group survival rate up to 87% 5 year, and nasopharyngeal carcinoma patient survival rate is 37.7% only in 5. Jian Shao point out, evaluate nasopharyngeal carcinoma patient, classify significant before the treatment while being clinical forever, it is expected to change the present therapeutic tactics. For example as to low the intersection of nasopharyngeal carcinoma and patient that endanger, may adopt the gentle healing solution while being clinical; As to high patient that endanger, should adopt positive method, ray dosage to strengthen radiotherapy while being clinical, set chemotherapy free, combine in addition, to treat etc. the intersection of molecule and target. He points out, this achievement also needs to carry on prospective clinical research to further confirm it is to nasopharyngeal carcinoma patient individual's clinical using value treating at the same time. Thesis of this research has already been issued in the clinical authoritative technical magazine " clinical oncological magazine " of making a diagnosis and giving treatment of tumour.


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